If a girl smiles at me, is she interested in me?

Oscar writes, "I am in college and have noticed two girls in class sometimes smile and laugh when they look at me. Sometimes when I make a comment in class they laugh. I know that some girls like to have fun. I do not want to misread people or take things seriously. How should I view their behavior?"

Yes, in 90% of cases this is a good sign, especially if the laugh is as if they are a little embarrassed, shy, playful, naughty, etc. and also exhibit other body language signs of interest and flirting. I am guessing that one of them is teasing the other about you or they both tease each other about you.

The only remote possibility that you need to eliminate is that these are not mean girls that are actually making fun of you for some reason.

So try to talk to them casually about something class-related and if they are warm and pleasant, I think it is a good idea to move forward to find which one of the two is actually interested in you.